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Fig. 7 | Chinese Neurosurgical Journal

Fig. 7

From: The role of FAM111B in the malignant progression and molecular regulation of human glioma through the PI3K/Akt pathway

Fig. 7

FAM111B regulated glioma cell proliferation, migration, and invasion via the PI3K/AKT pathway. A–C Western blot showing the PI3K/AKT pathway-related protein levels after using a PI3K inhibitor in SNB19 cells. D, E Transwell assay showing the number of invasive SNB19 glioma cells after treatment with a PI3K inhibitor. Magnification × 20. G, F Wound healing assay showing the amount of open area remaining in SNB19 cells after treatment with a PI3K inhibitor. Magnification × 4. H, I Colony formation assay showing the colony formation number of SNB19 cells after treatment with a PI3K inhibitor. Magnification × 1. According to the mean and standard deviation *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001. ns, not significant

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Chinese Neurosurgical Journal

ISSN: 2057-4967

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