Fig. 5

FAM111B promotes glioma cell tumorigenesis in vivo. A Nude mice were subcutaneously inoculated with SNB19 cells transfected with FAM111B-overexpressing viral vectors and negative control viral vectors. B Subcutaneous tumors in nude mice derived from SNB19 cells transfected with FAM111B-overexpressing viral vectors and negative control viral vectors. C, D Upregulated FAM111B expression in SNB19 cells of nude mice; subcutaneous xenograft volume and mass significantly increased. According to the mean and standard deviation *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001. ns, not significant