From: Extubation timing and risk of extubation failure in aneurysmal subarachnoid hemorrhage patients
 | Total | EF | None-EF | p value |
---|---|---|---|---|
Characteristics | n = 335 | n = 46 | n = 289 |  |
Age, years | 53.8 ± 10.3 | 56.0 ± 9.4 | 53.5 ± 10.5 | 0.588 |
Sex | 0.727 | |||
 Female | 190 (56.7) | 25 (54.3) | 165 (57.1) |  |
 Male | 145 (43.3) | 21 (45.7) | 124 (42.9) |  |
Comorbidities | ||||
 Smoking | 59 (17.6) | 9 (19.6) | 50 (17.3) | 0.708 |
 Drinking | 31 (9.3) | 7 (15.2) | 24 (8.3) | 0.133 |
 Hypertension | 156 (46.6) | 26 (56.5) | 130 (45.0) | 0.145 |
 Diabetes | 24 (7.2) | 4 (8.7) | 20 (6.9) | 0.665 |
 Hyperlipemia | 9 (2.7) | 3 (6.5) | 6 (2.1) | 0.083 |
 Respiratory disease | 4 (1.2) | 1 (2.2) | 3 (1.0) | 0.510 |
 Coronary disease | 10 (3.0) | 2 (4.3) | 8 (2.8) | 0.559 |
 Prior infarction | 22 (6.6) | 5 (10.9) | 17 (5.9) | 0.205 |
 Prior hemorrhage | 2 (0.6) | 1 (2.2) | 1 (0.3) | 0.135 |
Admission characteristics | ||||
 Onset to admission (days) | 2 (1–3) | 1 (0–2) | 2 (0–4) | 0.005 |
 Brain herniation | 10 (3.0) | 2 (4.3) | 8 (2.8) | 0.559 |
H–H grade | 0.01 | |||
 1 | 40 (11.9) | 3 (6.5) | 37 (12.8) |  |
 2 | 193 (57.6) | 24 (52.2) | 169 (58.5) |  |
 3 | 5 (1.5) | 3 (6.5) | 2 (0.7) |  |
 4 | 97 (29.0) | 16 (34.8) | 81 (28.0) |  |
WFNS grade | < 0.001 | |||
 1 | 142 (42.4) | 8 (17.4) | 134 (46.4) |  |
 2 | 135 (40.3) | 23 (50.0) | 112 (38.8) |  |
 3 | 12 (3.6) | 5 (10.9) | 7 (2.4) |  |
 4 | 32 (9.6) | 9 (19.6) | 23 (8.0) |  |
 5 | 14 (4.2) | 1 (2.2) | 13 (4.5) |  |
mFS | 0.016 | |||
 1 | 90 (26.9) | 4 (8.7) | 86 (29.8) |  |
 2 | 83 (24.8) | 13 (28.3) | 70 (24.) |  |
 3 | 45 (13.4) | 6 (13.0) | 39 (13.5) |  |
 4 | 117 (34.9) | 23 (50.0) | 94 (32.5) |  |
Hospital course and complications | ||||
 Time of extubation |  |  |  | 0.012 |
 Ultra-early stage (< 24 h) | 267 (79.7) | 43 (93.5) | 224 (77.5) |  |
 Early stage (≥ 24 h) | 68 (20.3) | 3 (6.5) | 65 (22.5) |  |
 Delayed cerebral ischemia | 70 (20.9) | 31 (67.4) | 39 (13.5) | < 0.001 |
 Hydrocephalus | 7 (2.1) | 3 (6.5) | 4 (1.4) | 0.024 |
 Length of hospital stay (days) | 13.7 ± 8.1 | 17.0 ± 8.9 | 13.2 ± 7.8 | 0.004 |
 Disability at discharge | 2877 (23.5) | 27 (65.9) | 50 (17.4) | < 0.001 |
 Hospital mortality | 7 (2.1) | 5 (10.9) | 2 (0.7) | < 0.001 |