Table 6 Multivariable Cox regression of predictors for survival after progression in TCGA
Variables | OS | PFS | SAP | |||
|---|---|---|---|---|---|---|
HR (95%CI) | p value | HR (95%CI) | p value | HR (95%CI) | p value | |
Age | ||||||
< 60 vs. ≥ 60 | 1.28 (0.88–1.86) | 0.20 | 1.01 (0.75–1.36) | 0.94 | 1.47 (1.00–2.17) | 0.05 |
MGMT methylation | ||||||
Yes vs. no | 0.49 (0.33–0.74) | 0.00 | 0.71 (0.52–0.97) | 0.03 | 0.64 (0.43–0.94) | 0.03 |
IDH1 Mutation | ||||||
Yes vs. no | 0.45 (0.19–1.06) | 0.07 | NA | NA | 0.32 (0.13–0.76) | 0.01 |
Therapy | ||||||
Standard vs. unstandard | 0.44 (0.27–0.71) | 0.00 | 0.72 (0.49–1.06) | 0.10 | 0.62 (0.38–1.02) | 0.06 |