Table 4 Univariate Cox analysis of factors for OS, PFS, and SAP in TCGA
Variables | OS | PFS | SAP | |||
|---|---|---|---|---|---|---|
HR (95%CI) | p value | HR (95%CI) | p value | HR (95%CI) | p value | |
Age | ||||||
< 60 vs. ≥ 60 | 1.80 (1.40–2.31) | 0.00 | 1.33 (1.06–1.67) | 0.14 | 1.73 (1.35–2.23) | 0.00 |
Gender | ||||||
Male vs. female | 1.01 (0.79–1.31) | 0.92 | 1.017 (0.80–1.28) | 0.89 | 0.99 (0.77–1.28) | 0.92 |
TCGA subtype | 1.05 (0.93–1.18) | 0.44 | 1.01 (0.91–1.13) | 0.81 | 1.06 (0.94–1.19) | 0.34 |
MGMT methylation | ||||||
Yes vs. no | 0.46 (0.32–0.66) | 0.00 | 0.71 (0.52–0.97) | 0.03 | 0.55 (0.39–0.78) | 0.00 |
IDH1 mutation | ||||||
Yes vs. no | 0.48 (0.24–0.99) | 0.05 | 0.80 (0.42–1.52) | 0.50 | 0.42 (0.21–0.86) | 0.02 |
Therapy | ||||||
Standard vs. unstandard | 0.50 (0.38–0.66) | 0.00 | 0.60 (0.47–0.78) | 0.00 | 0.65 (0.50–0.85) | 0.00 |